The cardiomyocyte mineralocorticoid receptor plays a critical role in cardiac disease.

阻断矿化皮质激素受体（MR）的药物可以预防心脏病和高血压。矿化皮质激素受体对肾上腺激素有反应。我们已经证明，这种效果部分是由于心肌细胞的MR阻断。这一新发现正在被进一步探索，以了解MR在正常生理和疾病中心肌细胞中的确切作用。了解核磁共振在不同组织中的作用将有助于开发针对心脏病的组织特异性治疗方法。

Drugs that block the mineralocorticoid receptor (MR), which responds to adrenal hormones, protect against heart disease and hypertension. We have shown that this effect is in part due to MR blockade in heart muscle cells. This novel finding is being explored further to understand the precise role of the MR in heart muscle cells in normal physiology and in disease. An understanding of the role of the MR in different tissues will enable development of tissue specific treatments for heart disease.