The mechanisms underlying pneumoviral-induced angiogenesis of the lung and its impact on the asthmatic response.
The mechanisms underlying pneumoviral-induced angiogenesis of the lung and its impact on the asthmatic response.
肺病毒诱导的肺部血管生成的机制及其对哮喘反应的影响。
批准号：
nhmrc : 510715
负责人：
Prof Judy Black
金额：
$37.65万
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2008
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2008-01-01 至 2012-12-31
中文摘要
翻译
哮喘是一种严重的呼吸系统疾病，导致肺部结构改变和呼吸困难，并经常因呼吸道病毒而加重。我们已经证明，新生小鼠的病毒感染会导致肺部新血管的生长(这是在人类哮喘患者中看到的特征)。该项目将调查涉及的机制，并确定这一特征作为治疗靶点的潜力。
英文摘要
Asthma, is a serious respiratory disease resulting in structural changes to the lung and breathing difficulties, and is often compounded by respiratory viruses. We have shown that viral infection of newborn mice causes the growth of new blood vessels in the lungs (a feature seen in human asthmatics). This project will investigate the mechanisms involved and determine the potential of this feature as a therapeutic target.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Ongoing uncoupled research fellowship
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批准号：nhmrc : 158200
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项目类别：NHMRC Research Fellowships
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资助金额：$41.45万
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财政年份：2001
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负责人：Prof Judy Black
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依托单位：
Airway hyperresponsiveness in vitro- molecular mechanisms
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批准号：nhmrc : 990232
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项目类别：NHMRC Project Grants
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资助金额：$83.21万
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财政年份：1999
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负责人：Prof Judy Black
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依托单位：
海外基金
