A BubR1-centred network for non-invasively measuring human oocyte quality

卵母细胞质量是妊娠结局最重要的决定因素。因此，选择最好的卵母细胞进行IVF等生育治疗将大大提高成功率并降低成本。我们已经确定了主要的卵母细胞调节器，并应用新的数字技术来测量这些调节器在一个单一的卵母细胞。该项目将应用这些专业知识开发新的方法来评估卵母细胞的潜力，从而告知其是否适合用于生育治疗。

Oocyte quality is the most important determinant of pregnancy outcome. Selecting the best oocytes for fertility treatments like IVF would therefore greatly improve success rates and reduce costs. We have identified master oocyte regulators and have applied novel digital technology to measure these regulators in a single oocyte. This project will apply this expertise to develop new approaches for evaluating an oocyte’s potential thereby informing its suitability for use in fertility treatment.