Assessment of microcirculatory impairment in reperfused acute myocardial infarction by invasive coronary hemodynamic measurements and cardiac magnetic resonance imaging: modulation by exenatide

本研究旨在通过使用压力线和心脏磁共振成像测量血流，评估心脏病发作期间和之后心肌小血管的健康状况。心脏病发作时，心肌内的小血管可能由于缺氧和白细胞激活而受伤。本研究调查了一种新药艾塞那肽对小血管和白细胞的影响，并确定它是否可能减轻对心肌和小血管的损害程度。

This study aims to assess the health of small blood vessels of the heart muscle during and following a heart attack by measuring blood flow with a pressure wire and with cardiac magnetic resonance imaging. Small blood vessels within the heart muscle may become injured due to lack of oxygen and white cell activation during a heart attack. This study investigates the effect of a new agent, exenatide, on small blood vessels and white cells and determines whether it might lessen the degree of damage to heart muscle and small blood vessels.