Betacellulin: defining a novel sub-type in schizophrenia
Betacellulin: defining a novel sub-type in schizophrenia
批准号:
nhmrc : 2001907
负责人:
金额:
$90.75万
依托单位国家:
澳大利亚
项目类别:
Ideas Grants
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2023-12-31
中文摘要
精神分裂症是一种严重的终身精神障碍,影响世界人口的0.7%,只有部分有效的对症治疗。其原因尚不清楚,因此目前无法开发治疗方法。一个有希望的候选者是β细胞素,一种在精神分裂症患者的大脑和血液中非常减少的生长因子。关于它在大脑中的作用知之甚少,该项目旨在确定其与精神分裂症的相关性,作为开发新治疗方法的一步。
英文摘要
Schizophrenia is a severe lifelong mental disorder affecting 0.7% of the world population with only partially effective symptomatic treatments. Its cause is unknown and thus cures cannot be developed currently. A promising candidate is betacellulin a growth factor which is very reduced in the brain and blood of people with schizophrenia. Little is known about its role in the brain and this project seeks to identify its relevance to schizophrenia as a step to develop new treatments.
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