Bioactive and biodegradable scaffold and novel graft source for the repair of large segmental bone defects

创伤和肿瘤引起的大面积骨缺损的治疗仍然是骨科医生面临的挑战。该项目结合了一个成熟的支架，可以定制，以满足患者的具体要求与一个新的移植物来源，可以在最小的痛苦和发病率的显着量收获。将在先前建立的临床前模型中评价这种新型组织工程方法，该模型反映了具有挑战性的临床场景的严重程度。

The treatment of large bone defects arising from trauma and tumour remains a challenge to orthopaedic surgeons. This project combines a well-established scaffold that can be custom-made to address patient specific requirements with a novel source of graft that can be harvested in significant volumes with minimal pain and morbidity. This novel tissue engineering approach will be evaluated in a previously established pre-clinical model that reflects the severity of challenging clinical scenarios.