Stereotaxic frame for monkey research

NSERC设备资金的申请是为了获得一个立体定位框架和显微操作器，用于绿色猴的神经解剖学追踪实验，该实验在一个名为：多感觉整合的皮质通路的NSERC资助研究计划中描述。这是实现NSERC资助的研究目标所必需的基本设备。为了精确应用神经解剖示踪剂和制备绿色猴脑的立体定位图谱，需要使用高标准立体定位框架获得立体定位坐标。1404型立体定位仪可用于从灵长类动物到小鼠的各种动物。1404型包括一个Kopf 1430型立体定位框架、四个1460型三维电极操作器，每个操作器均配有一个1770型标准电极保持器;还包括一个1210型安装底板、1225型通用旋转支架、1245型猫/猴适配器（带适配器板）和一套851型标准实心耳杆。除了这一基本设备外，我们还要求提供一个865型35 mm偏置耳杆和立管块，允许颞部手术入路，这将有助于在猴的听觉皮层中放置示踪剂注射。我们还需要一个1211型底板。这是一个便携式安装板，重量只有7磅，带有一个用于安装框架的插座。

This application for NSERC equipment funding is to acquire a stereotaxic frame and micromanipulators for neuroanatomical tract tracing experiments in the Green monkey described in a funded NSERC research program entitled: Cortical pathways for multisensory integration. This is a basic piece of equipment that will be necessary for the fulfillment of the research objectives funded by NSERC. Stereotaxic coordinates obtained with a high standard stereotaxic frame is needed for the precise application of neuroanatomical tracers and for the preparation of a stereotaxic atlas of the Green monkey brain. The Model 1404 Stereotaxic Instrument can be used for a wide variety of animals from primates to mice. The 1404 model consists of a Kopf Model 1430 stereotaxic frame, four model 1460 three-dimensional electrode manipulators, and each with a model 1770 Standard electrode holder; also included are a model 1210 mount base plate, model 1225 Universal swivel stand, Model 1245 Cat/Monkey adaptor with adaptor plate and one set of Model 851 Standard solid ear bars. In addition to this basic equipment we ask for a Model 865 35 mm offset ear bars and riser block allowing for temporal surgical approaches which will be useful for placement of tracer injections in the auditory cortex in monkeys. We request also a Model 1211 Base plate. This is a portable mounting plate weighing only 7 lbs with a socket for mounting the frame.