Blood-Spinal Cord Barrier Structure and Function in Syringomyelia

脊髓空洞症是一种在脊髓内形成充满液体的囊肿的疾病。随着时间的推移，这些包囊会膨胀，导致瘫痪甚至死亡。脊髓空洞症与脊髓损伤和一些先天性疾病有关。在这个项目中，我们的目标是调查目前尚不清楚的包囊形成的根本原因。希望这些研究将提高我们对囊肿形成的了解，并促进更好的治疗策略的发展。

Syringomyelia is a disorder in which a fluid-filled cyst forms within the spinal cord. These cysts expand over time resulting in paralysis or even death. Syringomyelia occurs in association with spinal cord injury and a number of congenital conditions. In this project we aim to investigate the underlying cause of cyst formation, which is currently unknown. It is hoped that these studies will improve our understanding of cyst formation and facilitate development of better treatment strategies.