Brain Connectivity Imaging Markers to Confirm Diagnosis for Bipolar vs. Unipolar Depression – A Connectome Approach.

鉴别双相情感障碍和单相抑郁症是一个重大的临床挑战。这种误诊阻碍了最佳的临床护理，并产生了许多有害的后果，如自残、自杀机会增加、预后不良以及与这种疾病相关的更高的医疗费用。该项目将为使用磁共振成像准确识别双相情感障碍提供迫切需要的进展，并消除准确诊断的关键障碍之一。

Differentiating Bipolar disorders from Unipolar Depression is a major clinical challenge. This misdiagnosis hinders optimal clinical care and has many deleterious consequences such self-harm, increased chances of suicide, poor prognosis, and greater health care costs related to this disorder. This project will provide urgently-needed advance in accurate identification of Bipolar disorders using Magnetic Resonance Imaging and remove one of the key obstacles to accurate diagnosis.