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Ecological and phylogenomic insights into infectious diseases in animals

Ecological and phylogenomic insights into infectious diseases in animals
对动物传染病的生态学和系统发育学见解
批准号:
DE240100388
负责人:
Dr Daniel Knight
金额:
$30.39万
依托单位国家:
澳大利亚
项目类别:
Discovery Early Career Researcher Award
财政年份:
2024
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2024-01-01 至 2026-12-31

项目摘要

项目成果

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中文摘要
翻译
该项目旨在解决我们对艰难梭菌的理解中的主要知识差距,艰难梭菌是动物严重胃肠道疾病的主要原因。该项目有望确定C. difficile感染的澳大利亚马,研究了C.艰难梭菌菌株引起的马疾病,并开发一种新的工具,增强基因组跟踪的C。在动物中很难。这些结果将支持兽医部门改善C.动物中的艰难感染,通过降低与C相关的发病率和死亡率来提供长期的社会经济效益。澳大利亚马和牲畜的艰难感染。
英文摘要
This project aims to address major knowledge gaps in our understanding of Clostridium difficile, a leading cause of severe gastrointestinal disease in animals. The project is expected to define the epidemiology of C. difficile infection in Australian horses, characterise the genetic and phenotypic traits of C. difficile strains causing equine disease and develop a new tool for enhanced genomic tracking of C. difficile in animals. These outcomes will support strategies by the veterinary sector to improve the detection, prevention and control of C. difficile infections in animals, providing long-term socio-economic benefits arising from reduced incidence and mortality associated with C. difficile infections in Australian horses and livestock.
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会议论文
A One Health approach to assessing the threat of Clostridium difficile to Australia’s biosecurity: a genomic investigation of human, animal and environmental isolates
  • 批准号:
    nhmrc : GNT1138257
  • 项目类别:
    Early Career Fellowships
  • 资助金额:
    $31.88万
  • 财政年份:
    2018
  • 负责人:
    Dr Daniel Knight
  • 依托单位:
海外基金