Carving psychosis at its biological joints

精神病显著增加了全球疾病负担，如果将精神分裂症、分裂情感性障碍和双相情感障碍一并考虑在内，则影响到超过3%的人口。这些情况在家庭中聚集，遗传风险因素不符合传统的诊断类别。我的工作采用基于大脑的分类技术来推导精神病的亚型，这些亚型剖析和/或跨越诊断类别，以调查精神病的可改变的遗传和环境风险因素。

Psychosis contributes significantly to global disease burden, affecting more than 3% of the population when schizophrenia, schizoaffective disorder, and bipolar disorders are considered together. These conditions aggregate within families, and genetic risk factors do not conform to traditional diagnostic categories. My work employs brain-based classification techniques to derive subtypes of psychosis that dissect, and/or span the diagnostic categories, for investigation of modifiable genetic and environmental risk factors for psychosis.