Roles of emerging pollutants in spreading antimicrobial resistance

抗菌素耐药性是一项日益严重的全球性挑战，但环境因素对抗菌素耐药性传播的影响了解甚少。根据我最近的发现和模型微生物生态系统的紧密整合，该项目旨在调查环境污染物对原位生态群落中抗菌素耐药性定植和传播的影响。该项目预计将在复杂生态系统中抗菌素耐药性研究的前沿产生新的知识。研究结果应提供与抗菌素耐药性相关的环境因素的深刻机制理解，并应用于One Health的抗菌素耐药性风险管理。

Antimicrobial resistance is a growing global challenge, yet the impact of environmental agents on the spread of antimicrobial resistance is poorly understood. Drawing on my recent findings and a tight integration of a model microbial ecology system, this project aims to investigate the impact of environmental pollutants on the colonisation and spread of antimicrobial resistance in situ ecological communities. This project expects to generate new knowledge at the forefront of research into antimicrobial resistance in a complex ecosystem. The outcomes should provide a deep mechanistic understanding of environmental factors associated with antimicrobial resistance, with applications to antimicrobial resistance risk management for One Health.