CAN PRIORITY ALLOCATION OF DECEASED DONOR KIDNEYS BASED ON EPLET AND BROAD HLA-ANTIGEN MATCHING IMPROVE KIDNEY TRANSPLANT POTENTIAL, REDUCES IMMUNOGENICITY AND IMPROVE HEALTH OUTCOMES IN INDIGENOUS KIDNEY TRANSPLANT CANDIDATES?

尽管肾移植已被证明可以改善慢性肾病（CKD）患者的预期寿命，但与非土著患者相比，土著CKD患者在移植前等待的时间是非土著患者的两倍，排斥反应和感染风险分别增加了3倍，导致移植物丢失和死亡。更好地了解土著患者的免疫组成可能有助于减少并发症的风险并提高生存率。

Although kidney transplantation has been shown to improve life expectancy in patients with chronic kidney disease (CKD), indigenous patients with CKD wait twice as long on the wait-list before transplant and have up to a 3-fold increased risk of rejection and infections resulting in graft loss and death respectively compared to non-indigenous patients. A better understanding of the immunological make-up of indigenous patients may help to reduce the risk of complications and improve survival.