The Role of Crim1 in Cardiovascular Development

冠状动脉疾病是澳大利亚最大的单一死亡原因，通常表现为心脏病发作和心绞痛。先天性心脏病是最常见的出生缺陷。我们已经确定了一种名为Crim1的基因，它对心脏和冠状动脉的发育非常重要。研究该基因如何发挥作用将有助于更好地了解先天性心脏病，并可能为治疗方法再生受损的心脏组织奠定基础。

Coronary artery disease is the largest single cause of death in Australia, and commonly manifests as heart attack and angina. Congenital heart disease is the most common birth defect. We have identified a gene, Crim1, that is important for heart and coronary artery development. Investigating how this gene functions will lead to a greater understanding of congenital heart disease and may lay the foundation for therapeutics to regenerate damaged hear tissue.