The cellular biology of turnip mosaic virus
The cellular biology of turnip mosaic virus
批准号:
3452-2008
负责人:
Laliberté, JeanFrancois
金额:
$3.72万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31
中文摘要
对于许多正链RNA[(+)RNA]病毒,RNA复制发生在细胞质膜泡中。在过去的几年里,我的研究团队已经证明,与芜菁花叶病毒(TuMV)基因组(VPG)相关的蛋白质可以与几种病毒和宿主蛋白质相互作用,特别是翻译因子。我们发现,其中许多相互作用发生在VPG的前体形式6K-VPG-Pro诱导的复制小泡中。在这项研究方案中,我希望扩大我们对含有病毒复制复合体的囊泡的理解。更具体地说,我希望阐明它们的内容和结构,并研究它们的起源和在细胞内的运动。
英文摘要
For many positive-strand RNA [(+) RNA] viruses, RNA replication occurs within cytoplasmic membranous vesicles. Over the past years, my research team has shown that the protein linked to the genome (VPg) of Turnip mosaic virus (TuMV) interacts with several virus and host proteins, notably translation factors. We have found that many of these interactions are taking place in replication vesicles induced by 6K-VPg-Pro, a precursor form of VPg. In this research proposal, I wish to extend our comprehension of the vesicles harbouring the virus replication complex. More specifically, I wish to elucidate their content and architecture and study their genesis and movement within the cell.
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The cellular biology of turnip mosaic virus
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批准号:3452-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2011
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负责人:Laliberté, JeanFrancois
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依托单位:
The cellular biology of turnip mosaic virus
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批准号:3452-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2010
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负责人:Laliberté, JeanFrancois
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依托单位:
The cellular biology of turnip mosaic virus
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批准号:3452-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.72万
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财政年份:2009
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负责人:Laliberté, JeanFrancois
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依托单位:
Virus-host interaction: turnip mosaic virus and initiation of translation
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.31万
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财政年份:2006
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负责人:Laliberté, JeanFrancois
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依托单位:
Virus-host interaction: turnip mosaic virus and initiation of translation
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批准号:3452-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.31万
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财政年份:2005
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负责人:Laliberté, JeanFrancois
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依托单位:
Virus-host interaction: turnip mosaic virus and initiation of translation
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批准号:3452-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.31万
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Production of proteins of pharmaceutical interest in alfalfa: development of a virus expression vector
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负责人:Laliberté, JeanFrancois
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依托单位:
Virus-host interaction: turnip mosaic virus and initiation of translation
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批准号:3452-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.31万
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依托单位:
Virus-host interaction: turnip mosaic potyvirus and initiation of translation
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批准号:3452-1999
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项目类别:Discovery Grants Program - Individual
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Development of a viral replicon for plant gene expression
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财政年份:2002
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依托单位:
Virus-host interaction: turnip mosaic potyvirus and initiation of translation
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批准号:3452-1999
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.06万
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财政年份:2001
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负责人:Laliberté, JeanFrancois
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依托单位:
Development of a viral replicon for plant gene expression
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批准号:234752-2000
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项目类别:Strategic Projects - Group
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资助金额:$6.19万
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财政年份:2001
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依托单位:
Virus-host interaction: turnip mosaic potyvirus and initiation of translation
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批准号:3452-1999
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.06万
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财政年份:2000
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依托单位:
Development of a viral replicon for plant gene expression
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项目类别:Strategic Projects - Group
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资助金额:$6.19万
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负责人:Laliberté, JeanFrancois
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依托单位:
Virus-host interaction: turnip mosaic potyvirus and initiation of translation
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批准号:3452-1999
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.06万
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财政年份:1999
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负责人:Laliberté, JeanFrancois
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依托单位:
Turnip mosaic potyvirus and gene expression
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批准号:3452-1995
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.84万
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财政年份:1998
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依托单位:
Turnip mosaic potyvirus and gene expression
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批准号:3452-1995
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资助金额:$1.68万
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财政年份:1997
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依托单位:
Turnip mosaic potyvirus and gene expression
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依托单位:
Turnip mosaic potyvirus and gene expression
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资助金额:$1.68万
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依托单位:
Plant molecular pharming: application for the development of an experimental recombinant subunit vaccine against human respiratory syncytial virus
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批准号:133864-1992
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项目类别:Strategic Projects - Group
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资助金额:$1.52万
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财政年份:1994
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