Role of spontaneous activity in the formation of functional cortical circuits in vivo.

大脑中的神经元连接在一起，形成支撑大脑功能的电路。为了正确地连接，大脑皮层神经元依赖于自发活动，在自发活动中，神经元以特定的模式发射，以找到并形成正确的大脑皮层回路。该项目旨在了解自发的大脑皮层活动如何调节大脑连接和大脑皮层发育。这项工作将使我们了解神经发育障碍以及优化大脑发育的方法。

Neurons in the brain wire together to from circuits that underpin brain function. In order to wire correctly, cortical neurons rely on spontaneous activity, where ensembles of neurons fire in specific patterns, to find and form their correct cortical circuits. This project aims to understand how spontaneous cortical activity regulates brain wiring and cortical development. The work will inform our understanding of neurodevelopmental disorders and ways to optimise brain development.