Schizophrenia: Reversal of atypical antipsychotic drug-induced obesity and its related metabolic disorders
Schizophrenia: Reversal of atypical antipsychotic drug-induced obesity and its related metabolic disorders
批准号:
nhmrc : 1027493
负责人:
Dr Francesca Fernandez-Enright
金额:
$41.33万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2016-12-31
中文摘要
非典型抗精神病药物,如奥氮平,通常用于治疗精神分裂症等精神疾病。虽然这些药物是有效的,但它们的肥胖和代谢紊乱的副作用是导致服药严重缺乏依从性的主要障碍。该项目旨在为精神疾病患者开发更好的抗精神病药物,减少副作用,包括肥胖和代谢紊乱。
英文摘要
Atypical antipsychotic drugs such as olanzapine are commonly used to treat mental illnesses such as schizophrenia. While these drugs are effective, their side effects of obesity and metabolic disorders are a major hurdle leading to a serious lack of compliance in taking medication. This project aims to develop better antipsychotic treatment with reduced side-effects including obesity and metabolic disorders for mental illness patients.
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