Instrument for characterization of plymers and solute release kinetics
Instrument for characterization of plymers and solute release kinetics
批准号:
374799-2009
负责人:
Wu, XiaoYu(Shirley)
金额:
$5.51万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-01-01 至 2009-12-31
中文摘要
生物相容性聚合物已被广泛用于制造各种高级药物,如每日一次的血压控制药片,这种药物比传统药物提供更有效的治疗,副作用更小。聚合物的性质,如分子量和溶解速率,决定药物何时和多快起作用,从而影响此类药物的治疗效果。与小分子不同,在一次反应中制备的聚合物可以具有不同的分子量,并且一些聚合物在应用过程中会降解,从而控制治疗剂从药物中释放的速度。
英文摘要
Biocompatible polymers have been widely used to make various advanced medications such as once daily blood-pressure-controlling pills that provide more effective treatment with lower side effects than conventional medications. The properties of polymers such as molecular weight and dissolving rate determine when and how fast the medicine will take effect thus affecting the therapeutic benefit of such medications. Unlike small molecules, polymers prepared in one reaction can have different molecular weights, and some polymers degrade during application thus controlling the release rate of therapeutic agents from the medications.
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会议论文
Molecular mechanism of polymer dynamics and kinetics of solute transport in multicomponent systems
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批准号:170460-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.17万
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财政年份:2010
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
Molecular mechanism of polymer dynamics and kinetics of solute transport in multicomponent systems
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批准号:170460-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.17万
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财政年份:2009
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
Molecular mechanism of polymer dynamics and kinetics of solute transport in multicomponent systems
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批准号:170460-2008
-
项目类别:Discovery Grants Program - Individual
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资助金额:$2.17万
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财政年份:2008
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
Kinetics and mechanism of solute transport in heterogeneous polymer systems
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批准号:170460-2003
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项目类别:Discovery Grants Program - Individual
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资助金额:$1.97万
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财政年份:2007
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负责人:Wu, XiaoYu(Shirley)
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依托单位:
海外基金