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Targeting lipids regulated in a setting of physiological cardiac hypertrophy

Targeting lipids regulated in a setting of physiological cardiac hypertrophy
针对生理性心脏肥大中调节的脂质
批准号:
nhmrc : 1045585
负责人:
A/Pr Julie Mcmullen
金额:
$32.67万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2016-12-31

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中文摘要
翻译
现有的心力衰竭疗法在很大程度上延缓了心力衰竭的进展,而不是逆转疾病。因此,迫切需要能够改善衰竭心脏功能的新的治疗策略。本研究的主要目的是确定在“良好”的生理心脏生长环境中(如运动时发生)心脏分泌的脂质是否可以靶向恢复衰竭心脏的功能。
英文摘要
Existing heart failure therapies largely delay heart failure progression rather than reversing the disease. New therapeutic strategies with the ability of improving function of the failing heart are thus greatly needed. The primary goal of this study is to determine whether lipids that are secreted by the heart in a setting of “good” physiological heart growth (as occurs with exercise) can be targeted to restore function of the failing heart.
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Targeting a novel long non-coding RNA that is dysregulated in skeletal and cardiac muscle disease
  • 批准号:
    nhmrc : 1127336
  • 项目类别:
    Project Grants
  • 资助金额:
    $42.4万
  • 财政年份:
    2017
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Targeting a new regulator of cardiac pathology to protect the heart from cardiac dysfunction and arrhythmia
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    nhmrc : 1125514
  • 项目类别:
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  • 资助金额:
    $49.01万
  • 财政年份:
    2017
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Identification of novel secretory factors from the heart as new targets for metabolic disease
  • 批准号:
    nhmrc : 1121806
  • 项目类别:
    Project Grants
  • 资助金额:
    $58.93万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Julie Mcmullen
  • 依托单位:
Identifying and developing novel therapeutic approaches for heart disease
  • 批准号:
    nhmrc : 1078985
  • 项目类别:
    Research Fellowships
  • 资助金额:
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  • 财政年份:
    2015
  • 负责人:
    A/Pr Julie Mcmullen
  • 依托单位:
海外基金