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The use of dosing software with Bayesian forecasting to improve antimicrobial-plasma concentrations in the Intensive Care Unit

The use of dosing software with Bayesian forecasting to improve antimicrobial-plasma concentrations in the Intensive Care Unit
使用贝叶斯预测剂量软件来提高重症监护病房的抗菌血浆浓度
批准号:
nhmrc : 2002981
负责人:
金额:
$7.74万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Postgraduate Scholarships
财政年份:
2021
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2021-01-01 至 2022-12-31

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中文摘要
翻译
诸如DSBF之类的新兴技术能够帮助临床医生选择能够达到治疗感染所需的目标抗菌药物浓度的给药方案。我们将开展一项临床试验,研究DSBF提高ICU患者抗菌药物浓度的能力。这项研究的结果可能会导致临床医生被赋予一个新的强大的验证工具,以改善ICU感染患者的治疗结果。
英文摘要
Emerging technologies such as DSBF is capable of assisting clinicians with selecting dosing regimens that achieve the target antimicrobial concentrations needed for treating infections. We will conduct a clinical trial to investigate the ability of DSBF to improve antimicrobial concentrations of patients in the ICU. The results of this study may lead to clinicians being given a new powerful validated tool for improving the treatment outcomes of patients suffering from infections in the ICU.
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