Translational Studies in Malaria

消灭疟疾的势头日益增强，需要控制抗药性寄生虫，这意味着需要新的药物和疫苗。在本奖学金中，我将使用我开发的人类疟疾挑战系统来测试疟疾新药和疫苗是否有效，足以证明其充分发展。在这个系统中，健康的志愿者被故意感染疟疾，然后在他们生病之前被治愈。

The growing momentum towards elimination of malaria and the need to control of drug-resistant parasites means that new drugs and vaccines are needed. In this Fellowship I will use the human malaria challenge system that I have developed to test whether new drugs and vaccines for malaria are working sufficiently well to justify their full development. In this system healthy volunteers are deliberately infected with malaria and then cured before they become unwell.