Treating Wernicke-Korsakoff syndrome.

wernickke - korsakoff综合征是由于硫胺素缺乏引起的一种常见且经常未确诊的神经系统疾病。这种情况会导致认知和神经功能障碍，主要影响酒精依赖者。虽然我们对硫胺素治疗这种疾病的最佳剂量还没有足够的了解，但韦尼克-科萨科夫综合征是可以用硫胺素治疗的。本项目拟开展两项对照试验，评价硫胺素治疗Wernicke-Korsakoff综合征的疗效。

Wernicke-Korsakoff syndrome is a common and frequently undiagnosed neurological disease due to thiamine deficiency. The condition leads to cognitive and neurological disability and mostly affects people with alcohol dependence. Wernicke-Korsakoff syndrome is eminently treatable with thiamine, although we have insufficient knowledge regarding the best dose of thiamine to treat the condition. This project proposes two controlled trials to evaluate treatment effectiveness of thiamine for Wernicke-Korsakoff syndrome.