Computational musculoskeletal modelling for orthopaedic applications

在加拿大，每年进行的全膝关节置换术（TKR）手术数量在过去十年中急剧增加，并将随着人口老龄化而继续增加。 虽然TKR手术通常能有效缓解术前疼痛，但相当一部分接受者不能完全恢复活动能力，许多人仍然难以完成日常任务。 这降低了生活质量，同时给卫生保健系统带来越来越大的负担，是这项工作的动力。

In Canada, the number of total knee joint replacement (TKR) surgeries performed per year has increased dramatically over the last decade and will continue to increase as the population ages. Although TKR surgery is generally effective in alleviating pre-surgical pain, a significant percentage of recipients don't recover full mobility and many continue to have difficulty with daily tasks. This reduces quality of life while placing an ever increasing burden on the health care system and is the impetus for this work.