Understanding how group 2 innate lymphoid cells in early life regulate postnatal lung development and susceptibility to chronic respiratory diseases
Understanding how group 2 innate lymphoid cells in early life regulate postnatal lung development and susceptibility to chronic respiratory diseases
批准号:
nhmrc : GNT1156898
负责人:
金额:
$50.1万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
早期呼吸道感染导致的肺生长受损对呼吸健康产生负面影响,并可能导致哮喘和肺气肿的发展。识别和开发促进肺正常健康发育的因素可能会导致预防和治疗呼吸系统疾病的新策略。我们已经确定了一种新类型的细胞,我们认为这种细胞对肺发育至关重要。这可能会在未来带来可观的健康和经济效益。
英文摘要
Impaired lung growth that results from respiratory infections in early life negatively impacts on respiratory health and may lead to the development of asthma and emphysema. The identification and exploitation of the factors that promote normal healthy lung development may lead to new strategies to prevent and treat respiratory diseases. We have identified a new type of cell that we think are critical for lung development. This may have substantial health and economic benefits in the future.
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