UNDERSTANDING THE BENEFITS AND LIMITATIONS OF METAPHASE II SPINDLE TRANSFER

线粒体DNA（mtDNA）疾病是从母亲的卵子传播给她的孩子。然而，受影响的mtDNA水平在她的卵子中不同。因此，携带者不会知道新生儿是否患有这些疾病。线粒体捐赠为夫妇提供了一个不受影响的孩子的可能性。我们将进行最全面的线粒体捐赠研究，使用其相关方法之一，以确定它是否产生健康的胚胎和后代。

Mitochondrial DNA (mtDNA) diseases are transmitted from a mother's eggs to her children. However, the levels of affected mtDNA differ amongst her eggs. Consequently, a carrier would not know if the newborn child were to suffer from these diseases. Mitochondrial Donation offers couples the potential to have an unaffected child. We will undertake the most comprehensive study of mitochondrial donation using one of its associated approaches to determine if it produces healthy embryos and offspring.