Vasoactive nutrients to promote healthy ageing in postmenopausal women
Vasoactive nutrients to promote healthy ageing in postmenopausal women
批准号:
nhmrc : 1106170
负责人:
金额:
$41.03万
依托单位国家:
澳大利亚
项目类别:
Targeted Calls
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2019-12-31
中文摘要
与情绪和认知障碍相关的大脑循环功能不良,可能会因年龄增长和绝经后雌激素缺乏而进一步恶化。我的研究将确定,补充植物雌激素两年后,白藜芦醇或染料木素是否可以通过增强脑血管扩张功能来抵消与更年期相关的情绪和精神表现损害,以及改善的幅度在更年期早期和晚期是否有所不同。
英文摘要
Poor circulatory function in the brain, associated with mood and cognitive disturbances, can be further exacerbated by ageing and estrogen deprivation at postmenopause. My research will determine whether phytoestrogen supplementation with either resveratrol or genistein for 2 years can counteract menopause-related impairments in mood and mental performance by enhancing cerebral vasodilator function and whether the magnitude of improvement differs between early and late menopausal years.
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