In vivo evaluation of the safety and efficacy of a novel chitosan gel in the reduction of adhesions following abdominal surgery in both animal and human models

高达95%的腹部手术患者会出现腹部粘连，近五分之一的患者因疼痛、胃肠功能减退和肠梗阻需要再次住院。新开发的壳聚糖凝胶已被证明是有效的控制出血和减少粘连后鼻窦手术。这些项目现在将探索它在腹部手术中的应用。壳聚糖凝胶每年有可能使数百万患者受益，并大大减轻我们卫生系统的负担。

Up to 95% of abdominal surgery patients will develop adhesions within the abdomen, with nearly 1 in 5 requiring hospital readmission for pain, reduced gastrointestinal function and bowel obstruction. Newly developed Chitodex gel has been shown to be effective in the control of bleeding and the reduction of adhesions following sinus surgery. These projects will now explore its use in abdominal surgery. Chitodex gel has the potential to benefit millions of patients each year and drastically lessen the burden on our health system.