Discovery Projects - Grant ID: DP210100665

自噬依赖的细胞和组织缺失的调节。该项目旨在阐明在动物发育过程中调节自噬依赖的树突状细胞死亡的新机制。它将把果蝇遗传学的力量与多学科方法结合起来，如蛋白质组学、生物信息学和细胞生物学。鉴于自噬的保守性，这一结果将提供具有广泛生物学意义的高度热门和令人兴奋的新知识。该项目将有助于建立国际合作，提高澳大利亚S在一个重要研究领域的竞争力和声誉，并为HDR学生提供一系列领域的技能培训。从长远来看，这些研究成果可能会转化为农业、粮食生产和人类健康结果的改善。

Regulation of autophagy dependent cell and tissue deletion. This project aims to elucidate novel mechanisms that regulate autophagy-depdendent cell death during animal development. It will combine the power of Drosophila genetics with multidisciplinary approaches, such as proteomics, bioinformatics and cell biology. Given the conserved nature of autophagy the oucomes will provide highly topical and exciting new knowledge of broad biological significance. The project will help establishing international collaborations, enhancing Australia’s competitiveness and reputation in an important area of research, and provide training of HDR students in skills across a range of areas. In the long-term the research findings may translate into improved agriculture, food production and human health outcomes.