Radioisotope counting facility

该RTI要求购买两台设备，这些设备将成为放射性同位素计数设施的一部分。该设施将成为环境基因组学高级研究中心（CAREG）共同实验室设施的一部分，并将由该单位管理，供本提案的7名申请人、其他CAREG成员（迄今为止有21名）和渥太华大学主校区需要放射性同位素计数设施的成员使用。鉴于加拿大的立法要求，放射性样品的运输受到严格监管，在缺乏有效计数设施的情况下，由申请人监督的至少35个HQPs的工作将处于危险之中。该请求（74698美元，包括3.41% HST）用于购买Tri-Carb 2910TR液体闪烁计数器（LSC）和WIZARD2伽马计数器（GC）。LSC取代了2001年购买的一种计数器，该计数器现已由其制造商停产；GC取代了1989年购买的过时且无法维修的设备。尽管技术不断改进，但使用放射性同位素评估途径通量、受体结合和药物发现仍然是“金标准”。这两种设备都被大量用于常规分析，尽管多年来它们一直很好地服务于共同申请人，很少进行重大维修，但任何一种设备的灾难性故障都将对用户的工作造成重大打击。

This RTI requests the purchase of two pieces of equipment that will become part of a Radioisotope Counting Facility. The Facility will be part of the Common Laboratory Facilities of the Centre for Advanced Research in Environmental Genomics (CAREG) and will be managed by this unit for the use of the 7 applicants of this proposal, for the other CAREG members (21 to date) and those on the main campus of uOttawa requiring radioisotope counting facilities. Given Canadian legislative requirements, the transportation of radioactive samples is tightly regulated and in the absence of an effective counting facility, the work of at least 35 HQPs supervised by the applicants would be in jeopardy. The request ($74698 including 3.41% HST) is for the purchase of a Tri-Carb 2910TR Liquid Scintillation Counter (LSC) and a WIZARD2 Gamma Counter (GC). The LSC replaces a counter purchased in 2001 which has now been discontinued by its manufacturer; the GC replaces equipment purchased in 1989 which is obsolete and can no longer be repaired. Although technologies continue to improve, the use of radioisotopes for assessing pathway flux, receptor binding and drug discovery remains the 'gold standard'. Both pieces of equipment are heavily used for routine analyses and although they have served the co-applicants well with few major repairs over the years, a catastrophic failure of either piece would be a major blow to the work done by the users.