Synthetic Molybdenum Enzymes

合成钼酶。该项目旨在生产合成钼(Mo)酶，这是一种小分子，与至关重要的钼掺杂物？钼酶具有相同的结构和功能属性。这些普遍存在的酶对动植物健康、涉及碳、氮和硫的自然循环以及全球气候控制和大气反照率(反射率)至关重要；因此，它们对商业、环境和社会产生重大影响。这项研究将对酶活性部位的基本钼硫化学提供迫切需要的见解，并为减少酶功能障碍的负面影响和设计新的商业催化剂提供参考。

Synthetic Molybdenum Enzymes. This project aims to produce synthetic molybdenum (Mo) enzymes, small molecules that share structural and functional attributes with the crucially important molybdopterin?Mo enzymes. These ubiquitous enzymes are essential for plant and animal health, natural cycles involving carbon, nitrogen and sulfur, and global climate control and atmospheric albedo (reflectance); consequently, they impact heavily on commerce, the environment and society. The study will provide urgently needed insights into the fundamental Mo?sulfur chemistry of the enzyme active sites and inform efforts to reduce the negative impacts of enzyme dysfunction and the design of new commercial catalysts.