Survival of and interactions between microorganisms in environmental biofilms

大肠杆菌是世界范围内最常用的粪便指示生物之一，一些致病菌株可以是水媒病原体。我们所知道的大部分关于E。大肠杆菌生物膜是基于在实验室条件下生长的K-12菌株。目前对生物膜的形成、环境和O 157 E的存活和扩散知之甚少。大肠杆菌菌株。已知rpoS对于某些细菌物种的生物膜发育和扩散是重要的。然而，rpoS对非K12菌株的生物膜形成和分散的作用尚不清楚。本文研究了归化E.大肠杆菌的生物膜基质，并将有助于了解和预防大肠杆菌的爆发。淡水系统中的大肠杆菌。

Escherichia coli is one of the most commonly used fecal indicator organisms worldwide and some pathogenic strains can be waterborne pathogens. Most of what we know about E. coli biofilm is based on the K-12 strain grown under laboratory conditions. Little is known about biofilm development, survival and dispersal of environmental and O157 E. coli strains under environmental conditions. The rpoS is known to be important for biofilm development and dispersal for some bacterial species. However, the role of rpoS on biofilm formation and dispersal of non-K12 strains is not clear. This proposal studies the persistence and detachment of naturalized E. coli in biofilm matrices and will contribute to the understanding and prevention of outbreaks of E. coli in fresh water systems.