Establishment of in vivo and in vitro models for systematic tissue-specific epigenomic mapping
Establishment of in vivo and in vitro models for systematic tissue-specific epigenomic mapping
批准号:
241928
负责人:
Okada Hitoshi
金额:
$7.28万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2011
资助国家:
加拿大
项目状态:
已结题
起止时间:
2011-11-01 至 2012-11-01
中文摘要
越来越清楚的是,表观基因组变化在不改变潜在dna序列的情况下调节基因表达,显著促进人类健康,包括癌症、肥胖和癌症的发病、进展和治疗反应。
英文摘要
It is increasingly clear that epigenenomic changes, which serve to regulate gene expression without altering the underlying DNA sequence, significantly contribute human health including onset, progression, and therapeutic response of cancer, obesity and a
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