Multi-wavelength Patterned Illuminator for Optogenetic Stimulation of Neurons
Multi-wavelength Patterned Illuminator for Optogenetic Stimulation of Neurons
批准号:
439829-2013
负责人:
Woodin, Melanie
金额:
$0.56万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31
中文摘要
突触抑制对大脑正常运作至关重要。我的实验室专注于理解特定神经元群在产生这种突触抑制中的作用。 我们正在使用最近开发的“光遗传学”技术进行这些实验。光遗传学允许研究人员在“开关的一瞬间”激活或沉默遗传靶向神经元;这项技术的革命性力量是导致它在2010年被命名为年度自然方法的原因。在这项拨款申请中,我们要求资金购买光遗传学刺激设备,我们可以将其与我们现有的电生理设备结合使用。
英文摘要
Synaptic inhibition is critical for the brain to function properly. My lab is focused on understanding the role of particular groups of neurons in generating this synaptic inhibition. We are preforming these experiments using the recently developed technique of 'optogenetics'. Optogenetics allows researchers to activate or silence genetically targeted neurons at the 'flick-of-a-switch'; the revolutionary power of this technique is what led to it being named the Nature Method of the Year in 2010. In this grant application we are requesting funds to purchase optogenetics stimulation equipment, which we can use in combination with our existing electrophysiology equipment.
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会议论文
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2020-04793
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2022
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负责人:Woodin, Melanie
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依托单位:
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2020-04793
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项目类别:Discovery Grants Program - Individual
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资助金额:$4.23万
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财政年份:2021
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负责人:Woodin, Melanie
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依托单位:
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2015-03752
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.77万
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财政年份:2019
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负责人:Woodin, Melanie
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依托单位:
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2015-03752
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.77万
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财政年份:2018
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负责人:Woodin, Melanie
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依托单位:
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2015-03752
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.77万
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财政年份:2017
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负责人:Woodin, Melanie
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依托单位:
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2015-03752
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.77万
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财政年份:2016
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负责人:Woodin, Melanie
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依托单位:
Inhibitory Synaptic Plasticity
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批准号:RGPIN-2015-03752
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.77万
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财政年份:2015
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负责人:Woodin, Melanie
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依托单位:
Optical Uncaging of Neurotransmitters
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批准号:472348-2015
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$8.65万
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财政年份:2014
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负责人:Woodin, Melanie
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依托单位:
Disinhibition-mediated long-term potentiation
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批准号:293196-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.91万
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财政年份:2014
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负责人:Woodin, Melanie
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依托单位:
Disinhibition-mediated long-term potentiation
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批准号:293196-2010
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
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财政年份:2013
-
负责人:Woodin, Melanie
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依托单位:
Disinhibition-mediated long-term potentiation
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批准号:293196-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2012
-
负责人:Woodin, Melanie
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依托单位:
Disinhibition-mediated long-term potentiation
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批准号:396034-2010
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项目类别:Discovery Grants Program - Accelerator Supplements
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资助金额:$2.91万
-
财政年份:2012
-
负责人:Woodin, Melanie
-
依托单位:
Disinhibition-mediated long-term potentiation
-
批准号:293196-2010
-
项目类别:Discovery Grants Program - Individual
-
资助金额:$2.91万
-
财政年份:2011
-
负责人:Woodin, Melanie
-
依托单位:
Disinhibition-mediated long-term potentiation
-
批准号:396034-2010
-
项目类别:Discovery Grants Program - Accelerator Supplements
-
资助金额:$2.91万
-
财政年份:2011
-
负责人:Woodin, Melanie
-
依托单位:
Disinhibition-mediated long-term potentiation
-
批准号:396034-2010
-
项目类别:Discovery Grants Program - Accelerator Supplements
-
资助金额:$2.91万
-
财政年份:2010
-
负责人:Woodin, Melanie
-
依托单位:
Disinhibition-mediated long-term potentiation
-
批准号:293196-2010
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.91万
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财政年份:2010
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负责人:Woodin, Melanie
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依托单位:
Nucleofection of cultured hippocampal neurons
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批准号:390105-2010
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$1.79万
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财政年份:2009
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负责人:Woodin, Melanie
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依托单位:
Spike-timing dependent plasticity of GABAergic synapses in the hippocampus
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批准号:293196-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.09万
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财政年份:2009
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负责人:Woodin, Melanie
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依托单位:
Activity-Induced Plasticity of Inhibitory Synapses
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批准号:299453-2004
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项目类别:University Faculty Award
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资助金额:$2.91万
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财政年份:2008
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负责人:Woodin, Melanie
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依托单位:
Spike-timing dependent plasticity of GABAergic synapses in the hippocampus
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批准号:293196-2007
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项目类别:Discovery Grants Program - Individual
-
资助金额:$2.09万
-
财政年份:2008
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负责人:Woodin, Melanie
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依托单位:
海外基金