Novel tools for controlling singlet oxygen in cellular systems.
Novel tools for controlling singlet oxygen in cellular systems.
批准号:
355548-2012
负责人:
Heyne, Belinda
金额:
$2.55万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-01-01 至 2013-12-31
中文摘要
图像是人们感知宇宙的主要手段。目前的技术已经改变了这种看法,这在生物科学中尤为明显,因为活细胞成像正在探索亚细胞结构和功能的奥秘。成像技术正在给生物学带来革命性的变化,因为它允许实时观察发生在生物体内的事件。不幸的是,对活体的成像几乎保证了单线态氧的形成,这是一种高度活性和毒性的分子氧形式,对被观察的生物是危险的,并使从标本获得的数据恶化。
英文摘要
Images are the primary means by which people perceive the universe. Current technology has transformed this perception, as is particularly evident in the biological sciences, as live cell imaging delves into the mysteries of subcellular architecture and function. Imaging techniques are revolutionizing biology by permitting the observation of events in real-time, as they occur inside of living organisms. Unfortunately, the imaging of living organisms almost guarantees the formation of singlet oxygen, a highly reactive and toxic form of molecular oxygen, which is dangerous to the living organism being observed and which deteriorates the data obtained from the specimen.
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资助金额:$3.28万
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2018
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依托单位:
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批准号:RGPIN-2017-03824
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项目类别:Discovery Grants Program - Individual
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资助金额:$3.28万
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财政年份:2017
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负责人:Heyne, Belinda
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依托单位:
Novel tools for controlling singlet oxygen in cellular systems.
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批准号:355548-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2016
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负责人:Heyne, Belinda
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依托单位:
Novel tools for controlling singlet oxygen in cellular systems.
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批准号:355548-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2015
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负责人:Heyne, Belinda
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依托单位:
Novel tools for controlling singlet oxygen in cellular systems.
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批准号:355548-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2014
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负责人:Heyne, Belinda
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依托单位:
Novel tools for controlling singlet oxygen in cellular systems.
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批准号:355548-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.55万
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财政年份:2013
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负责人:Heyne, Belinda
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依托单位:
Use of fluorescent proteins as new photosensitizers in order to have a better control of singlet oxygen generation at specific subcellular location
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批准号:355548-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2010
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负责人:Heyne, Belinda
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依托单位:
Use of fluorescent proteins as new photosensitizers in order to have a better control of singlet oxygen generation at specific subcellular location
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批准号:355548-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2009
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负责人:Heyne, Belinda
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依托单位:
Use of fluorescent proteins as new photosensitizers in order to have a better control of singlet oxygen generation at specific subcellular location
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批准号:355548-2008
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项目类别:Discovery Grants Program - Individual
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资助金额:$2.33万
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财政年份:2008
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负责人:Heyne, Belinda
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依托单位:
Spectrofluorimeter instrument for the investigation of fluorescent protein photobleaching mediated by singlet oxygen
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批准号:359664-2008
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项目类别:Research Tools and Instruments - Category 1 (<$150,000)
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资助金额:$3.25万
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财政年份:2007
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负责人:Heyne, Belinda
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依托单位:
海外基金