An Accelerated Solvent Extraction System for the Laboratory for the Analysis of Natural and Synthetic Environmental Toxicants (LANSET).

天然和合成环境毒物分析实验室(LANSET)是渥太华大学的一个研究和培训设施，为渥太华大学和其他地方的更广泛的研究界定期分析各种天然和合成环境毒物。LANSET采用的分析方法主要包括用各种色谱和光谱分析方法分析植物提取物和环境样品。我们的天然产品和环境毒理学研究依赖于采用加速溶剂萃取(ASE)系统处理的样品。ASE允许从各种类型的样品中快速、高效地提取一系列分子。此外，该仪器是代谢物分析和已知化合物定量的关键步骤，我们已经发布了几种经过验证的方法来优化环境样品的提取。使用ASE，我们可以分析环境样品中的合成污染物(使用经过验证的药物、个人护理产品、类固醇雌激素、多环芳烃和其他方法)和藻类毒素(微囊藻毒素、类毒素、根瘤素)。

The Laboratory for the Analysis of Natural and Synthetic Environmental Toxicants (LANSET) is a research and training facility at the University of Ottawa that routinely analyzes a wide range of natural and synthetic environmental toxicants for the broader research community at the University of Ottawa and elsewhere. The analytical methodologies applied at LANSET mainly include the analysis of plant extracts and environmental samples by various chromatographic and spectrometric methods. Our natural product and environmental toxicology studies rely on samples processed with an Accelerated Solvent Extraction (ASE) system. The ASE allows for the rapid, and highly efficient extraction of a wide suite of molecules from a variety of sample types. In addition the instrument is a key step for metabolite profiling and quantification of known compounds and we have published several validated methods to optimize extraction of environmental samples. Using the ASE, we can analyze environmental samples for synthetic pollutants (with validated methods for pharmaceuticals, personal care products, steroidal estrogens, polyaromatic hydrocarbons, and others), and algal toxins (microcystins, anatoxins, nodularin).