Single cell analysis of telomerase activity and regulation
Single cell analysis of telomerase activity and regulation
批准号:
253363
负责人:
Chartrand Pascal
金额:
$45.05万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01
中文摘要
为了正常生长和分裂,正常细胞必须保持其基因组的完整性。端粒位于染色体的末端,对维持染色体的稳定性至关重要。端粒缩短导致基因组的不稳定性,并有利于癌症的发生。
英文摘要
In order to properly grow and divide, normal cells must maintain the integrity of their genome. Telomeres cap the ends of chromosomes and are essential to maintain their stability. Telomere shortening leads to genomic instability and favors the rise of ca
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Studying telomeres maintenance by telomerase using live cell imaging
-
批准号:388224
-
项目类别:Operating Grants
-
资助金额:$62.14万
-
财政年份:2018
-
负责人:Chartrand Pascal
-
依托单位:
4th Canadian Symposium on Telomeres and Genomic Integrity
-
批准号:372804
-
项目类别:Miscellaneous Programs
-
资助金额:$0.73万
-
财政年份:2017
-
负责人:Chartrand Pascal
-
依托单位:
Mechanisms regulating mRNA localization and translational control
-
批准号:279097
-
项目类别:Operating Grants
-
资助金额:$48.12万
-
财政年份:2013
-
负责人:Chartrand Pascal
-
依托单位:
The roles of MBNL proteins in the pathogenesis of myotonic dystrophy
-
批准号:286116
-
项目类别:Operating Grants
-
资助金额:$8.25万
-
财政年份:2013
-
负责人:Chartrand Pascal
-
依托单位:
海外基金