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Subcellular mRNA localization and translational control in plant cells

Subcellular mRNA localization and translational control in plant cells
植物细胞中的亚细胞 mRNA 定位和翻译控制
批准号:
203706-2011
负责人:
Muench, Douglas
金额:
$2.26万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31

项目摘要

项目成果

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相关文献

中文摘要
翻译
mRNA的亚细胞定位是基因表达的重要转录后调节因子,其在细胞功能和发育中具有关键作用。mRNA定位在发育过程中建立空间模式、促进蛋白质靶向细胞器和产生细胞极性方面至关重要。虽然mRNA定位在动物和真菌细胞中得到了很好的研究,但对植物细胞中的过程知之甚少。我的研究计划旨在提供mRNA定位及其在植物细胞中相关的翻译控制的更深入的了解。本文提出了三个与mRNA定位和翻译调控相关的研究目标。
英文摘要
The subcellular localization of mRNAs is an important post-transcriptional regulator of gene expression that has critical roles in cellular function and in development. mRNA localization is essential in establishing spatial patterning during development, facilitating targeting of proteins to organelles, and generating cellular polarity. Although mRNA localization is well studied in animal and fungal cells, very little is known about the process in plant cells. My research program is aimed at providing a deeper understanding of mRNA localization and its associated translational control in plant cells. Three research objectives related to mRNA localization and translational control are described in this proposal.
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Post-transcriptional control of gene expression and its role in plant responses to developmental and environmental cues
  • 批准号:
    RGPIN-2016-06505
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.55万
  • 财政年份:
    2022
  • 负责人:
    Muench, Douglas
  • 依托单位:
Post-transcriptional control of gene expression and its role in plant responses to developmental and environmental cues
  • 批准号:
    RGPIN-2016-06505
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.55万
  • 财政年份:
    2021
  • 负责人:
    Muench, Douglas
  • 依托单位:
Development of a passive, plant-based naphthenic acid remediation technology for treatment of oil sands process-affected water.
  • 批准号:
    545169-2019
  • 项目类别:
    College - University Idea to Innovation Grants
  • 资助金额:
    $7.26万
  • 财政年份:
    2021
  • 负责人:
    Muench, Douglas
  • 依托单位:
Development of a passive, plant-based naphthenic acid remediation technology for treatment of oil sands process-affected water.
  • 批准号:
    545169-2019
  • 项目类别:
    College - University Idea to Innovation Grants
  • 资助金额:
    $8.08万
  • 财政年份:
    2020
  • 负责人:
    Muench, Douglas
  • 依托单位:
国内基金
海外基金
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  • 资助金额:
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  • 批准年份:
    2026
  • 负责人:
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  • 依托单位:
靶向子宫内膜癌的GCNT3 mRNA聚合物纳米递送系统的构建及转化研究
YBX1介导的HOXA9 mRNA稳定性影响c-MYC转录在胃癌进展中的机制研究
TET1介导GLI3 mRNA m5C去甲基化修饰负调控ABCA1促动脉粥样硬化
  • 批准号:
    2026JJ81712
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2026
  • 负责人:
    颜滢
  • 依托单位: