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Chemical tailoring of poly(ethylene oxide)-block-poly(ester) copolymers for drug delivery applications

Chemical tailoring of poly(ethylene oxide)-block-poly(ester) copolymers for drug delivery applications
用于药物输送应用的聚(环氧乙烷)-嵌段-聚(酯)共聚物的化学定制
批准号:
261196-2013
负责人:
Lavasanifar, Afsaneh
金额:
$2.11万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31

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中文摘要
翻译
这项研究的主要目的是设计和开发能够充分溶解药物,以适当的速度和位置释放药物,同时对人体安全应用的新型合成材料。这类化合物有望模仿生物运输系统的功能:在体内被识别为自身,携带足够数量的药物到其作用部位,在其细胞和分子靶标附近释放其货物,然后降解为生物相容的成分。合成生物材料具有结构易修饰、稳定性好、给药安全等优点,与生物材料相比具有一定的优势。
英文摘要
The main purpose of this research is to design and develop novel synthetic materials that can adequately solubilize drugs, release them in an appropriate rate and location, and at the same time, are safe for application in humans. Such compounds are expected to mimic the function of biological transport systems: be recognized as self within the body, carry adequate quantities of the drug to its site of action, release their cargo in the vicinity of their cellular and molecular targets and degrade to biocompatible components afterwards. Synthetic biomaterials are advantageous to their biological counterparts due to the ease of structural modifications, stability and safety of administration.
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Development of stimuli deformable lipid/polymer hybrid nano-materials for drug delivery applications
  • 批准号:
    RGPIN-2019-05979
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.35万
  • 财政年份:
    2022
  • 负责人:
    Lavasanifar, Afsaneh
  • 依托单位:
Development of stimuli deformable lipid/polymer hybrid nano-materials for drug delivery applications
  • 批准号:
    RGPIN-2019-05979
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.35万
  • 财政年份:
    2021
  • 负责人:
    Lavasanifar, Afsaneh
  • 依托单位:
Development of stimuli deformable lipid/polymer hybrid nano-materials for drug delivery applications
  • 批准号:
    RGPIN-2019-05979
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.35万
  • 财政年份:
    2020
  • 负责人:
    Lavasanifar, Afsaneh
  • 依托单位:
Development of stimuli deformable lipid/polymer hybrid nano-materials for drug delivery applications
  • 批准号:
    RGPIN-2019-05979
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.35万
  • 财政年份:
    2019
  • 负责人:
    Lavasanifar, Afsaneh
  • 依托单位:
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