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Mass spectrometry proteomic analysis of PTPN12 to elucidate its phosphatase role in tumor suppression and cell signalling

Mass spectrometry proteomic analysis of PTPN12 to elucidate its phosphatase role in tumor suppression and cell signalling
对 PTPN12 进行质谱蛋白质组分析,阐明其磷酸酶在肿瘤抑制和细胞信号传导中的作用
批准号:
279433
负责人:
Go Christopher D
金额:
$1.27万
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-02-01 至 2014-02-01

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中文摘要
翻译
PTPN12是一种磷酸酶蛋白,当它不能正常工作时,可以导致细胞成为致瘤性。在三阴性乳腺癌患者中发现有缺陷,三阴性乳腺癌是一种不容易通过特异性生物标志物识别的乳腺癌疾病。
英文摘要
PTPN12 is a phosphatase protein can cause cells to become tumorigenic when it is not working properly. It is found to be defective in patients with triple negative breast cancer, a type of breast cancer disease that is not easily identified by specific bi
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