Defining the causes of heterogeneous riboucleotide reductase gene transcription in response to DNA damage and anti-cancer drugs
Defining the causes of heterogeneous riboucleotide reductase gene transcription in response to DNA damage and anti-cancer drugs
批准号:
280186
负责人:
Kaern Mads
金额:
$26.54万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2016-03-01
中文摘要
药物治疗的结果可能因人而异。对模型系统的研究,如乳腺癌和肺癌细胞系,已经表明药物反应的变异性可以起源于单个细胞的水平,即使是在细胞水平上。
英文摘要
The outcome of drug therapy can vary significantly from one individual to the next. Studies of model systems, such as breast and lung cancer cell lines, have shown that variability in drug responses can originate at the level of individual cells, even und
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