A Varied Diet, Ageing, and the Evolution of Life Histories

这项研究旨在了解营养环境如何影响寿命及其演变。预期的成果是提高对衰老生物学的认识，包括确定饮食反应基因和生物途径。这些要素将包括未来关于衰老、代谢功能障碍和个性化营养的应用研究的目标。这项研究还将为寿命如何演变提供信息。由于寿命是一个基本的人口特征，这方面的知识将提高预测人口如何适应环境变化的能力。最后，通过方法创新，该项目还将提供新的统计工具，用于研究治疗如何影响死亡年龄的风险。

This research aims to understand how nutritional environments affect lifespan and its evolution. The expected outcomes are improved knowledge around the biology of ageing including the identification of diet-responsive genes and biological pathways. These elements will comprise targets for future applied studies on ageing, metabolic dysfunction and personalised nutrition. This study will also inform as to how lifespans evolve. Because lifespan is a fundamental demographic trait, this knowledge will improve ability to predict how populations adapt to environmental change. Lastly, through methodological innovation this project will also provide new statistical tools for studying how treatments affect the risk of death age specifically.