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Cholesterol Transbilayer Distribution in Mammalian cells: Mechanisms and Functions

Cholesterol Transbilayer Distribution in Mammalian cells: Mechanisms and Functions
哺乳动物细胞中胆固醇跨双层分布:机制和功能
批准号:
402010-2013
负责人:
Zha, Xiaohui
金额:
$1.97万
依托单位:
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-01-01 至 2015-12-31

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中文摘要
翻译
真核生物质膜(PM)以其磷脂在小叶之间的不对称分布而闻名。胆固醇是PM的另一个主要组成部分,但其双分子层分布仍不确定。目前,胆固醇被认为优先与外小叶中的SM结合形成脂质筏。
英文摘要
Eukaryotic plasma membrane (PM) is known for its assymetric distribution of phospholipids between the leaflets. Cholesterol is another major component of the PM Yet, its bilayer distribution remains uncertain. Currently, cholesterol is thought to preferentially bind to SM in the outer leaflet to form lipid raft.
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The role of long acyl chain sphingolipids in plasma membrane lateral organizations of mammalian cells
  • 批准号:
    RGPIN-2018-04229
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $3.5万
  • 财政年份:
    2022
  • 负责人:
    Zha, Xiaohui
  • 依托单位:
The role of long acyl chain sphingolipids in plasma membrane lateral organizations of mammalian cells
  • 批准号:
    RGPIN-2018-04229
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.75万
  • 财政年份:
    2021
  • 负责人:
    Zha, Xiaohui
  • 依托单位:
The role of long acyl chain sphingolipids in plasma membrane lateral organizations of mammalian cells
  • 批准号:
    RGPIN-2018-04229
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.75万
  • 财政年份:
    2020
  • 负责人:
    Zha, Xiaohui
  • 依托单位:
The role of long acyl chain sphingolipids in plasma membrane lateral organizations of mammalian cells
  • 批准号:
    RGPIN-2018-04229
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $1.75万
  • 财政年份:
    2019
  • 负责人:
    Zha, Xiaohui
  • 依托单位:
海外基金