new horizons in the chemistry of 3D metal pincer complexes

这项提议要求资金支持一项研究计划，该计划旨在促进我们对一组被称为“配体”的化学实体与金属相互作用方式的理解。除了基础发现和对科学进步的贡献外，我们还希望利用我们研究的金属-配体相互作用类型来发明可能发生有用的化学转化的过程。本课程属于有机金属化学的一般领域。顾名思义，这个学术领域的中心主题是围绕金属元素和有机分子的结合以及这种有机金属化合物的不同性质。有机金属化合物涉及许多大规模的商业生产过程，如醋酸(食醋的主要成分)、工业酒精和酸、聚酯、聚乙烯，甚至一些药物的生产。在大多数情况下，这些工艺的商业可行性和竞争力源于催化现象，即使用少量关键的化学转换器来生产非常大量的产品。加拿大在金属有机化学和催化方面在工业化国家中享有竞争地位。 我们计划在蒙特利尔大学进行的研究包括 开发新的有机镍化合物家族，并研究它们将低价值化学品转化为附加值产品的能力。我们过去的研究导致了基于一类称为钳形配体的配体的新催化剂的开发；这些催化剂可以将简单的化学物质转化为更有价值的产品。我们建议在一些有希望的方向上扩展我们的研究。这项工作将对加拿大学生进行现代化学技术方面的培训。这类培训已使30多名我们的前学生在工业、学术和公共部门找到了工作。

This proposal requests funds to support a research program aimed at advancing our understanding of the way in which a group of chemical entities called "ligands" interact with metals. In addition to making fundamental discoveries and contributing to the progress of science, we also hope to put to use the type of metal-ligand interactions we study for inventing processes that will make possible useful chemical transformations. This program falls in the general area of organometallic chemistry. As the name implies, the central theme of this area of scholarship revolves around the combination of metallic elements and organic molecules and the different properties of such organometallic compounds. Organometallic compounds are involved in many large scale commercial processes for the production of commodities such as acetic acid (the main ingredient of vinegar), industrial alcohols and acids, polyester, polyethylene, and even some medications. In most cases, the commercial viability and competitiveness of these processes is due to the phenomenon of catalysis, that is the use of a small quantity of key chemical transformers to produce a very large quantity of products. Canada enjoys a competitive position among industrialized nations in organometallic chemistry and in catalysis. The research studies that we plan to carry out at the University of Montreal consist of developing a new family of organonickel compounds and studying their abilities to transform lower value chemicals to value-added products. Our past studies have resulted in the development of new catalysts based on a family of ligands called pincer ligands; these catalysts can transform simple chemicals into more valuable products. We propose to extend our studies in a number of promising directions. This work will result in the training of Canadian students in modern chemical techniques. This type of training has allowed more than 30 of our ex-students to find employment in various industrial, academic, and public sectors.