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Altered Activity and Telomere Association of Disease-associated Variants in the Human Telomerase "Insertion in Fingers" Domain

Altered Activity and Telomere Association of Disease-associated Variants in the Human Telomerase "Insertion in Fingers" Domain
人类端粒酶“插入手指”域中疾病相关变异的活性改变和端粒关联
批准号:
324237
负责人:
MacNeil Deanna
金额:
$0.07万
依托单位国家:
加拿大
项目类别:
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-01-01

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中文摘要
翻译
端粒酶通过遗传稳定来防止细胞死亡,在许多癌症中通常是活跃的,但在正常细胞中不存在。这使它成为开发抗癌疗法时考虑的一个很好的酶。特别是,学习姿势
英文摘要
The telomerase enzyme protects against cell death through genetic stabilization, and is typically active in many cancers but absent from normal cells. This makes it a good enzyme to consider when developing anticancer therapies. In particular, studying po
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会议论文
Telomerase Regulation through Post-translational Modifications of Dyskerin
Telomerase Regulation through Post-translational Modification of Dyskerin
Telomerase Regulation through Post-translational Modifications of Dyskerin
  • 批准号:
    331385
  • 项目类别:
    Studentship Programs
  • 资助金额:
    $1.27万
  • 财政年份:
    2014
  • 负责人:
    MacNeil Deanna
  • 依托单位:
海外基金