Transduction of wild type mice with AAV2-alpha-synuclein-GFP drives expression of alpha-synuclein in the brain stem region that controls muscle atonia during REM sleep.
Transduction of wild type mice with AAV2-alpha-synuclein-GFP drives expression of alpha-synuclein in the brain stem region that controls muscle atonia during REM sleep.
批准号:
324334
负责人:
McKenna Dillon
金额:
$0.06万
依托单位:
依托单位国家:
加拿大
项目类别:
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-01-01
中文摘要
快速眼动(REM)睡眠是睡眠的一个阶段,在此期间会做梦,身体处于麻痹状态。这种麻痹的控制依赖于脑干中一个叫做蓝下(SubC)的区域。当SubC停止运作时,瘫痪就消失了
英文摘要
Rapid eye movement (REM) sleep is the stage of sleep during which dreaming occurs and the body is paralyzed. Control of this paralysis relies on an area of the brain stem called the subcoeruleus (SubC). When the SubC stops functioning, paralysis is lost a
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