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Nanoparticle-based anti-Myc cancer therapeutics

Nanoparticle-based anti-Myc cancer therapeutics
基于纳米颗粒的抗 Myc 癌症疗法
批准号:
462505-2014
负责人:
Shin, Jumi
金额:
$10.88万
依托单位:
依托单位国家:
加拿大
项目类别:
Collaborative Health Research Projects
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-12-31

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中文摘要
翻译
我们正在设计能对抗癌症的新药。这些药物是基于天然蛋白质,这是丰富的, 让你的身体发挥作用。我们利用这些基础材料来设计超级蛋白质药物。我们的一种药物 干扰细胞中一个已知的问题,导致癌症。我们的团队现在专注于如何使用纳米技术, 它们是微小的载体颗粒,可以将药物输送到癌细胞。一旦进入细胞,药物可以干扰 癌症网络我们已经证明,我们的策略可以在人类癌细胞实验中发挥作用,我们现在的目标是 在老鼠身上测试我们的药物加拿大公司BioVectra是我们的合作伙伴,参与了我们的研究,希望 将我们的新药用于人类癌症患者他们也很高兴能与我们合作,因为我们可以把概念 并设计针对其他蛋白质的额外药物,这些蛋白质在许多人类疾病中引起问题。
英文摘要
We are designing new drugs that can combat cancer. These drugs are based on natural proteins, which are abundant in your body and make your body function. We take these building blocks and design super protein drugs. One of our drugs interferes with a known problem in cells that can lead to cancer. Our team is now focusing on how to use nanotechnology, which are tiny carrier particles that can deliver the drug to cancer cells. Once inside the cells, the drug can interfere with cancer networks. We have shown that our strategy can work in human cancer cell experiments, and we are now aiming to test our drugs in mice. The Canadian company BioVectra is our partner and is involved in our studies with the hope of advancing our new drug to human cancer patients. They are also excited to work with us, because we can take the concepts described in this work and design additional drugs targeting other proteins that cause problems in many human diseases.
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Incorporating intrinsically disordered regions into rationally designed proteins that target DNA
  • 批准号:
    RGPIN-2020-05854
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.33万
  • 财政年份:
    2022
  • 负责人:
    Shin, Jumi
  • 依托单位:
Incorporating intrinsically disordered regions into rationally designed proteins that target DNA
  • 批准号:
    RGPIN-2020-05854
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.33万
  • 财政年份:
    2021
  • 负责人:
    Shin, Jumi
  • 依托单位:
Incorporating intrinsically disordered regions into rationally designed proteins that target DNA
  • 批准号:
    RGPIN-2020-05854
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.33万
  • 财政年份:
    2020
  • 负责人:
    Shin, Jumi
  • 依托单位:
Engineering & Evolution of Proteins that Target Specific DNA Sites
  • 批准号:
    RGPIN-2014-05632
  • 项目类别:
    Discovery Grants Program - Individual
  • 资助金额:
    $2.55万
  • 财政年份:
    2018
  • 负责人:
    Shin, Jumi
  • 依托单位:
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