Novel C. elegans and zebrafish models of neuronal nicotinamide-N-methyltransferase to study dopaminergic neurodegeneration underlying Parkinson's disease
Novel C. elegans and zebrafish models of neuronal nicotinamide-N-methyltransferase to study dopaminergic neurodegeneration underlying Parkinson's disease
批准号:
339108
负责人:
Schmeisser Kathrin
金额:
$9.29万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-11-01 至 2018-09-01
中文摘要
越来越多的证据表明,烟酸代谢的关键酶烟酰胺N-甲基转移酶(NNMT)与帕金森病(PD)的发生和进展有关。这一想法源于数据显示NNMT表达是重要的,
英文摘要
There is mounting evidence linking the enzyme nicotinamide N-methyltransferase (NNMT), a key enzyme of the niacin metabolism, to the development and progression of Parkinson's disease (PD). This idea arises from data showing that NNMT expression is signif
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