Signal processing for functional FD OCT

下一代FD OCT系统预计将不仅仅是结构成像，还将包括 功能成像。特别是，测量视网膜的偏振特性提供了重要的 仅在结构OCT图像中无法观察到的诊断信息。偏振敏感型FD OCT 需要分别检测光的两种偏振，通常指的是S偏振和p偏振。 实现这一点有不同的方法，例如，直接的实现是有两种 分开的分光计，S偏振和p偏振各一个。或者，分光计可以是 具有多光纤输入的定制设计，以及在同一探测器上的不同位置的成像光学元件。在……里面 无论哪种情况，都需要对每个探测器采集的干涉信号进行重新采样和归一化 偏振敏感处理。这需要执行非平凡的信号处理。此外， 尽管已经提出了对FD OCT数据进行偏振敏感处理的各种方法 从文献上看，这是主动算法信号处理发展的一个领域。 PPO在光谱仪设计和制造方面具有专业知识，但需要新的信号处理 偏振敏感型FD OCT的功能。发展偏振敏感OCT是中国的一项战略举措 为了扩大PPO的关注点，为功能成像提供FD OCT引擎，这将是 这一新兴市场应用具有显著的竞争优势。这项研究提案的目的是 是研究使用FD OCT成像的偏振敏感处理和可视化工具 通过米孜·费萨尔·贝格博士的一项新合作，还用于成像和无损检测 和P&P Optica Inc.。Beg博士在SFU开发的图像处理算法和方法 具有补充和满足PPO需求的巨大潜力。

The next generation of FD OCT systems are expected to grow beyond just structural imaging, and to include functional imaging. In particular, measurement of the polarization properties of the retina provides important diagnostic information that is not observable in the structural OCT image alone. Polarization sensitive FD OCT requires separate detection of the two polarizations of light, referred to commonly as the s and p polarizations. There are different ways of implementing this, for example a straight forward implementation is to have two separate spectrometers, one for each of the s and the p polarizations. Alternatively, the spectrometer could be custom designed with multi-fibre inputs, and imaging optics to different locations on the same detector. In either case, the interferometric signal acquired by each detector needs to be re-sampled and normalized for polarization sensitive processing. This requires non-trivial signal processing to be performed. Furthermore, although various approaches to polarization sensitive progressing of the FD OCT data have been proposed in the literature, this is an area of active algorithmic signal processing development. PPO has expertise in the spectrometer design and manufacturing, but requires new signal processing capabilities for polarization sensitive FD OCT. Develop of polarization sensitive OCT is a strategic move in order to expand the focus at PPO to deliver FD OCT engines for functional imaging, which would be a significant competitive advantage for this emerging market application. The purpose of this research proposal is to investigate polarization sensitive processing and visualization tools using FD OCT imaging for biological imaging and also for non-destructive testing (NDT) through a new collaboration between Dr. Mirza Faisal Beg and P&P Optica Inc. The image processing algorithms and approaches developed at SFU by Dr. Beg have significant potential to complement and address the needs of PPO.