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Role of Integrin-Linked Kinase in Mitotic Spindle dynamics and Centrosome clustering in cancer cells

Role of Integrin-Linked Kinase in Mitotic Spindle dynamics and Centrosome clustering in cancer cells
整合素连接激酶在癌细胞有丝分裂纺锤体动力学和中心体聚集中的作用
批准号:
179794
负责人:
Dedhar Shoukat R
金额:
$49.11万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2009
资助国家:
加拿大
项目状态:
已结题
起止时间:
2009-03-01 至 2014-03-01

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中文摘要
翻译
癌细胞分裂是不正常的。癌细胞通常会获得额外的中心体,这些中心体通常在细胞分裂过程中控制遗传物质适当地分离到子细胞中。额外的中心体使癌细胞容易受到细胞死亡的影响,但
英文摘要
Cancer cell division is abnormal. Cancer cells often acquire extra centrosomes which normally control proper segregation of genetic material into daughter cells during cell division. The extra centrosomes make cancer cells vulnerable to cell death, but ma
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Investigation of Neutrophil Extracellular Trap DNA ( NET-DNA) induced signaling in the progression of Pancreatic Ductal Adenocarcinoma
The Role of Microbiota and Immune Microenvironment in Breast Cancer Metastasis
  • 批准号:
    453393
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.37万
  • 财政年份:
    2021
  • 负责人:
    Dedhar Shoukat R
  • 依托单位:
The Role of Tumor Microenvironment in Cancer Progression: Identification and Therapeutic Intervention of Novel Targets
Role of ILK/Rictor complex in the TGF-b and Hippo signaling pathway mediated EMT, cancer stem cell function and tumor progression
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