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Systematic and comprehensive analysis of mutant p53 proteins in lung cancer in vitro and in vivo.

Systematic and comprehensive analysis of mutant p53 proteins in lung cancer in vitro and in vivo.
肺癌体内外突变p53蛋白的系统综合分析。
批准号:
364326
负责人:
Schramek Daniel
金额:
$0.0万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2017
资助国家:
加拿大
项目状态:
已结题
起止时间:
2017-02-01 至 2020-02-01

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中文摘要
翻译
P53是一种众所周知的肿瘤抑制因子,可以防止癌症的形成。它是癌症患者中最常见的突变基因。超过50%的人类肿瘤含有获得性p53突变或缺失。遗传的p53突变可能是Li-的基础
英文摘要
p53 is a well-known tumor suppressor that prevents cancer formation. It is the most commonly mutated gene in people who have cancer. More than 50% of human tumors contain an acquired mutation or deletion of p53. Inherited mutations of p53 can underlie Li-
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海外基金